منابع مشابه
Therapeutic approaches to the treatment of recurrent respiratory papillomatosis of the aerodigestive tract (a clinical study)
Recurrent respiratory papillomatosis (RRP) is a rare disease, characterized by recurrent proliferation of benign squamous cell papillomas in the larynx as well as in the other parts of the aerodigestive tract. We have compared different treatment options for RRP of the aerodigestive tract including surgical, conservative and combined approaches. A total of 43 patients with papillomatosis that r...
متن کاملGenital HPVs in the Aerodigestive Tract: Etiologic Association with a Subset of Oropharyngeal/Tonsillar Cancers and with Recurrent Respiratory Papillomatosis
The mucosal human papillomaviruses (HPVs) primarily infect the genital tract, but they also infect the mucosa lining the aerodigestive tract where they are etiologically linked to two clinical entities. The high-risk HPV type 16, which is responsible for about 50% of cervical cancers, is linked to a subset of oropharyngeal/ tonsillar cancers. Low-risk HPV types 6 and 11, which cause a large maj...
متن کاملExtraesophageal reflux and upper aerodigestive tract diseases.
Reflux disease can cause multiple disorders not only of the esophagus but also of the upper aerodigestive tract. In the last decade, an association between reflux disease and multiple head and neck diseases was described, including those of the larynx and pharynx as well as those of the nose, the sinuses and the middle ear. The present article summarizes these different diseases and possible pa...
متن کاملTobacco smoke induces CYP1B1 in the aerodigestive tract.
Several members of the P450 family, including cytochrome P450 1B1 (CYP1B1), can convert tobacco smoke (TS) procarcinogens, including benzo[a]pyrene (B[a]P), to carcinogenic intermediates. In this study we investigated the effects of TS condensate and B[a]P on the expression of CYP1B1 in vitro and in vivo. CYP1B1 mRNA and protein were induced by both TS condensate and B[a]P in cell lines derived...
متن کاملCetuximab activity in dysplastic lesions of the upper aerodigestive tract.
BACKGROUND High risk head and neck mucosal premalignancy has a malignant conversion rate of up to 40%, despite adequate surgical therapy. Epidermal Growth Factor Receptor (EGFR) blocking agents, including cetuximab, have shown activity in head and neck squamous cell carcinoma (HNSCC) and have potential for therapy in high risk premalignancy. METHODS We conducted a randomized, prospective, pha...
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ژورنال
عنوان ژورنال: The Laryngoscope
سال: 1982
ISSN: 0023-852X
DOI: 10.1288/00005537-198209000-00001